It was revealed that CCR5 was significantlydownregulated by JMJD1A siRNA transfection in polyI:Cstimulated THP1-Mφs, while CCR5 expression was notsignificantly influenced by JMJD1C siRNA transfection.The regulatory role of JMJD1A has been found to affectthe proliferation, migration, and invasion of cancer cellsin various cancer types (25-27). The gene discussed is CCR5; the disease is cancer.