Consistentwith our result, a group of scientists reported that ATOdecreased the gene expression level of Beclin1, LC3-IIand MAPK signaling pathways in U118-MG cells (29).Li et al. (34) by studying Beclin 1 and LC3II, indicatedthat inhibiting autophagy promotes the cytotoxic effect ofATO in glioblastoma cells. This evidence concerns the gene MAP1LC3A and glioblastoma.