Prior studies have stated that VEGF increases ELTD1 expression and DLL4‐Notch decreases the expression in normal vasculature; however, our study has demonstrated that this relationship may be more complex in the tumour environment.9 We were also able to significantly reduce Notch1 levels within the tumour and return them to near contralateral levels with our mAb treatment. The gene discussed is VEGFA; the disease is neoplasm.