AKT1 and neuroblastoma: Interestingly, YAP could also serve as a downstream target of Akt signalling.50, 51 YAP is identified as a substrate of Akt and can be phosphorylated by Akt, which attenuates p73‐mediated apoptosis.50 The Akt inhibitor Akt VIII decreased p‐YAP level and increased YAP level.51 Therefore, there may be a YAP‐Akt‐YAP feedback loop existing in the regulation of neuroblastoma proliferation.