Some studies have indirectly suggested that YAP and TAZ are activated in neuroblastoma and may be closely related to neuroblastoma invasion and metastasis.15, 16 For example, in recurrent neuroblastoma, a mutation in PTPN14 as a negative regulator of YAP is detected, thus, YAP activity may be increased in recurrent neuroblastoma.15 TAZ can promote the transformation of epithelial cells into mesenchymal cells and promote neuroblastoma invasion and metastasis.16 As a co‐transcription factor of TAZ, YAP may also have the similar effects on the invasion and metastasis of neuroblastoma. Here, PTPN14 is linked to neuroblastoma.