Figure 2a illustrates the score patterns for the example cancer genes MDM4 (R = 0.820, beta test p = 6.91 × 10–37), KRAS (R = 0.765, p = 1.66 × 10–29), CTNNB1 (R = 0.803, p = 1.92 × 10–34), and SMARCA4 (R = 0.664, p = 4.61 × 10–20) with unprocessed data (N = 147). The gene discussed is MDM4; the disease is cancer.