Since DNA damage in neurons has been reported in various neurodegenerative diseases [34,35], including PiD [36,37] and PSP [37], the mislocalization and coaggregation of BRCA1 with tau suggested in PiD and PSP in this study may also be involved in the progression of these diseases. The gene discussed is BRCA1; the disease is supranuclear palsy, progressive, 1.