Second, future studies are needed to determine whether BRCA1 also colocalizes with tau in other tauopathies, such as argyrophilic grain disease, chronic traumatic encephalopathy, tangle-only dementia, amyotrophic lateral sclerosis, and parkinsonism–dementia complex, and globular glial tauopathy [1]. This evidence concerns the gene BRCA1 and amyotrophic lateral sclerosis.