CAT and type 2 diabetes mellitus: Nonetheless, 5 also promoted the increase of the activity of antioxidant enzymes, including superoxide dismutase (SOD), catalase (CAT), and glutathione peroxidase (GSH-px) in liver tissues, and it increased levels of the phosphorylation of AMPK and Akt in muscle tissues (Table 1), suggesting that 5 can be developed as a therapeutic agent for type II diabetes [58].