In all, Galectin-3 and Galectin-1 support high fidelity and prolonged Ras signaling downstream to Raf or PI3-kinase, and they also control Ras-regulated tumor suppressor, e.g., Bcl2 or β-catenin, thereby supporting tumor survival [21,31,32]. The gene discussed is LGALS1; the disease is neoplasm.