The pro-inflammatory cytokine, IL-1β, provokes the epithelial–mesenchymal transition (EMT) of tumor cells due to activation of the IL-1β/interleukin 1 receptor type 1 (IL-1RI)/β-catenin signaling pathway [7] and recruits additional immune cells to the tumor site [6]. This evidence concerns the gene IL1R1 and neoplasm.