Despite the variable levels of LMP1 expression in NPC biopsies reported in the literature, which likely reflect the sensitivity and specificity of the methods of detection used to identify LMP1-positivity [67], it is widely believed that LMP1 expression plays an important role during the early disease process, both in the malignant transformation of nasopharyngeal epithelial cells, as well as recruiting and activating the characteristic inflammatory infiltrate. The gene discussed is PDLIM7; the disease is nasopharyngeal carcinoma.