IL-6-induced STAT3 phosphorylation levels were found to be increased in cells treated with follicle-stimulating hormone (FSH), luteinizing hormone (LH), 17β-estradiol or estrogen and it facilitated cell proliferation in human ovarian surface epithelial (HOSE) and ovarian cancer (OVCA) cell lines [59]. This evidence concerns the gene STAT3 and ovarian cancer.