However, in a neonatal mouse model of NEC, enteral administration of another HMO found in breast milk, 2’fucosyllactose (HMO-2’FL), resulted in the preservation of mesenteric perfusion and restored the expression of endothelial nitric oxide synthase (eNOS), a vasodilatory molecule necessary for intestinal perfusion [44]. This evidence concerns the gene NOS3 and necrotizing enterocolitis.