For the 56 SVR patients in the Peg-IFN/RBV arm, no predictors for HCC recurrence were found, and HCC recurrence history prior to antiviral therapy [HR: 4.210 (95% CI: 1.307–13.56), p = 0.0167] was the only predictor for HCC recurrence in non-SVR patients in the Peg-IFN/RBV arm. This evidence concerns the gene IFNA1 and hepatocellular carcinoma.