The authors analyzed a panel of 34 cytokines, chemokines, and growth factors in the SWF of breast cancer patients and found, that the concentrations of IP-10, IL-6, G-CSF, osteoponin, MIP-1 alpha, MIP-1 beta, and MCP1-MCAF were higher in more aggressive tumors. This evidence concerns the gene CSF3 and breast carcinoma.