However, our in vitro study results revealed that TSGH-8301 cells expressed the highest maspin protein levels among the four carcinoma cell lines (RT-4, HT1376, T24, and TSGH-8301), which indicated that maspin expression among the bladder carcinoma cell lines is dependent on the cell type but is not related to the extent of neoplasia in vitro. This evidence concerns the gene SERPINB5 and neoplasm.