Importantly, compared with HD/ASCs, both single and double positive RD/ASCs had lower basal ICAM-1 expression (Figure 1C), which, in addition, correlated moderately with TGF-β1 release by these cells (Figure S2, Supplementary Materials), suggesting that ICAM-1 may also have an impact on RD/ASC secretory function. The gene discussed is ICAM1; the disease is Huntington disease.