SOX2 and head and neck squamous cell carcinoma: Preliminary analyses of the human OSCC genome U133A array of the Toruner HNSCC cohort (n = 20) showed concomitant upregulation of CD47 (1.55-fold, p = 0.00003), SOX2 (1.40-fold, p = 0.01), and CD133 (1.13-fold, p = 0.06) in the OSCC tissues, compared to normal tissue group (Figure 3A).