While CRP was shown earlier to be elevated in patients with acute cardiac events (unstable angina pectoris, non-ST-elevation myocardial infarction, or ST-elevation myocardial infarction), neopterin did not differ between these patients, but was predictive for a higher risk of an adverse long-term outcome in patients with coronary artery disease compared to high CRP concentrations [12]. The gene discussed is CRP; the disease is coronary artery disorder.