A functional analysis revealed that miR-223 inhibited cell proliferation and inducted apoptosis in oral cancer cell lines, and also observed downregulated expression of STMN1 and IGF1R. Xu et al. [58] reported significant upregulated serum miR-483-5p expression in 101 oral cancer patients with respect to 103 healthy controls. Here, IGF1R is linked to lip and oral cavity carcinoma.