Western blot analysis, following protein immunoprecipitation of ccRCC tissue samples by anti-GSTO1 antibody, showed association of GSTO1 with RPS6 phospho-S235/236 and Akt phospho-S473, downstream effectors of PI3K/Akt/mTOR pathway (Figure 4, Figure S1). This evidence concerns the gene GSTO1 and nonpapillary renal cell carcinoma.