CD8A and lymphoma: Especially adenoviruses seem to be excellent vectors to elicit EBNA1-specific CD8+ T cell responses, and have in combination with DEC-205 targeting of EBNA1 or modified vaccinia virus Ankara (MVA) expressing EBNA1 induced long-lived CD8+ T cell responses in human DEC-205 transgenic mice that protected from EBNA1 expressing a syngeneic lymphoma challenge [80].