Sensitized T cells secrete interferon-gamma, which play a central role in the formulation and maintenance of granulomas, maintain TB in a dormant state for decades.[4] Radiological findings of previous TB infection, nodules and scars on chest radiography, are included as risk factors for reactivation of LTBI.[1] These findings could reflect the formation of granuloma developed by TB. This evidence concerns the gene IFNG and Granuloma.