Furthermore, the clinical representation of AS was highly inconstant, which would have overlapped with the Angelman-like syndrome, including Rett syndrome, Kleefstra syndrome, Mowat-Wilson syndrome, and FOXG1-related disorder.[6] The diagnosis of AS was based on typical clinical manifestations and/or genetic DNA sequence analysis.[7] However, genetic testing results could exhibit a deletion of maternal material or uniparental disomy of paternal material, which may distinguish AS from these. This evidence concerns the gene FOXG1 and atypical Rett syndrome.