To further investigate the novel relation of the triglyceride composition of HDL particles (and thereby potentially the inhibition of CETP) with incident CHD, we performed systematic analyses focusing on 3 fundamental measures that characterize the overall lipoprotein profile fairly well, namely, total serum triglyceride, HDL-C, and apolipoprotein B concentration, and gradually adjusted the association between HDL particle triglyceride composition and incident CHD. This evidence concerns the gene CETP and coronary artery disorder.