Given the existing evidence that mutations in MeCP2, the underlying cause of Rett Syndrome, may cause neurological dysfunction by specifically disrupting long gene expression in the brain, and previously reported overlaps between FMRP and MeCP2 targets, we tested the overlap of our CA1 FMRP target list with a set of genes that are transcriptionally repressed by MeCP2 (Gabel et al., 2015). Here, FMR1 is linked to Rett syndrome.