SOCS3 and cancer: By monitoring the phenotypes of these cells, we found that overexpression of SOCS3 rescued multiple malignant phenotypes induced by DANCR in both MCF10A and MCF7 cells, including cell viability (Fig. 8A,B), migration (Fig. 8C,D), invasion (Fig. 8E,F), EMT (Fig. 8G,H), and cancer stemness (Fig. 8I–L).