Previously, pathologic variants of PSP have been described.35 Of interest, that study found a higher density of cortical tau pathology in variants of PSP presenting with focal cortical syndromes compared with PSP-parkinsonism and PSP-PGF, a finding that is in line with differences in cortical atrophy seen in PSP-cortical vs PSP-subcortical groups in our study. The gene discussed is MAPT; the disease is supranuclear palsy, progressive, 1.