Using an AUC cutoff of at least 0.80 to represent high diagnostic accuracy, we confirmed the role of cognitive screening scales in differentiating CBS-AD from CBS-4RT and the role of cognitive screening scales, serum NF-L levels, and cortical volumetric MRI measures in differentiating PSP-subcortical from PSP-RS and PSP-cortical. Here, NEFL is linked to Alzheimer disease.