IFNB1 and multiple sclerosis: In addition to the information strategy adopted, it was observed that topics of great popular appeal also interfered with the increase of consultations, such as: “Exclusion of beta interferon for the treatment of multiple sclerosis” (4,846 suggestions) and “Guidelines for pregnant women: the Caesarean section operation” (3,706 suggestions) in 2015; and “PCDT for HIV Pre-Exposure Prophylaxis (PrEP)” (3,773 suggestions) and “Dimethyl fumarate for multiple sclerosis” (1,813 suggestions) in 2017.