Several vital lncRNAs, such as DANCR, MALAT1, and HOTAIR, have been identified as closely related to NPC progression.15, 16, 17 Recently, the aberrant expression of CYTOR has been reported in some types of cancers, including gastric cancer, hepatocellular carcinoma, and colon cancer, in which it may act as an oncogene.18, 19 However, the functional role and molecular mechanism of CYTOR in NPC remain vague. This evidence concerns the gene HOTAIR and colonic neoplasm.