They include cytokeratin and anti-endomysial antibody (epithelial markers), Desmin, myogenin (rhabdomyosarcoma), CD3, CD20, CD45, Tdt (lymphoma including lymphoblastic lymphoma markers), HMB 45, S100 protein, Melan-A (melanoma), neuron-specific enolase, chromogranin A, synaptophysin, and CD56 (neuroendocrine/ neuroectodermal differentiation) (8-9). The gene discussed is SYP; the disease is melanoma.