DKC1 and prostate cancer: DKC1 upregulation is associated with the poor prognosis of patients with prostate cancer,27 hepatocellular carcinoma,28 and neuroblastoma.29 Meanwhile, DKC1 acts as a tumour suppressor and inhibits the development of pituitary tumours by downregulating the translational level of p27.30 In this study, we will explore the role of DKC1 in CRC progression.