When neovascularisation is formed inside the tumour tissue, it provides a large amount of nutrients to the tumour cells, thereby causing the cells to grow rapidly and infiltrate into the surrounding tissues, and has a tendency to metastasise.45 Our studies showed that HUVECs’ ability to form the tube was enhanced in conditioned medium collected from HCT116 cells and DLD1 cells overexpressing DKC1 (Fig. 2j). The gene discussed is DKC1; the disease is neoplasm.