DKC1 and dyskeratosis congenita: Dyskeratosis congenita 1 (DKC1) gene was first discovered because its mutation caused dyskeratosis congenita (DC), which is an infrequent inherited syndrome, manifested as leukoplakia of oral, nail dystrophy, and unnatural reticulate skin pigmentation.7,8 Research has shown that the occurrence of DC can increase the incidence of many diseases, such as aplastic anaemia, bone marrow failure syndromes (BMFSs), and pulmonary fibrosis.