VEGF is an important proangiogenic factor that provides optimal matrix for tumour cell growth and new capillary network by enhancing vascular permeability and extravasation of fibrinogen, and VEGF stimulates proliferation of vascular endothelial cells and promotes angiogenesis.46 Our results confirmed that DKC1 can positively regulate VEGF expression. Here, DKC1 is linked to neoplasm.