In hypoxic conditions, the increase in the telomere length of mesenchymal stem cell can significantly stimulate mesenchymal stem cell proliferation49 and telomerase activity inhibition slowed cell proliferation in cervical cancer50 and glioma.51 Dyskerin is a key constituent of telomerase, and DKC1 maintains telomerase activity. This evidence concerns the gene DKC1 and central nervous system cancer.