The diagnostic accuracy of the six‐member panel of markers (HCCR, C‐myc, MDM2, miR‐21, miR‐223, and miR‐375) for cancer patients with TNM0‐I, Tis‐T1, and negative lymph node metastasis was 87%, 85%, and 84%, respectively (Figure 4 and Table 2). This evidence concerns the gene MDM2 and cancer.