LETMD1 and esophageal squamous cell carcinoma: Based on the expression levels of these nine significant markers (p53, p62, HCCR, C‐myc, MDM2, miR‐21, miR‐223, miR‐375, and miR‐100), we found that a panel of six plasma markers (HCCR, C‐myc, MDM2, miR‐21, miR‐223, and miR‐375) was able to effectively discriminate the ESCC patients from control individuals.