ZEB1 and glioblastoma: To further explore the possible mechanism through which LINC00511 could promote GBM progression by regulating ZEB1, FISH and subcellular fractionation were performed to examine its subcellular localization, which determine its function.33 Interestingly, the results of both showed that LINC00511 was primarily localized in the cytoplasm rather than nucleus of GBM cells (Figure 5A,B).