PTEN and cancer: miR‐144‐3p was located in 17q11.2, the region often amplified in NPC patients.44 In NPC, miR‐144‐3p was discovered to promote tumor migration and invasion by down‐regulating the tumor suppressor gene phosphatase and tensin homolog (PTEN) and activating the PI3K/Akt pathway.45 miR‐205‐5p have complex roles of oncogenicity and anti‐oncogenicity in different cancers.