PTEN and neoplasm: But in NPC, according to Nie G et al, it functioned as tumor‐promotor via targeting tumor protein p53‐inducible nuclear protein 1.46 miR‐17‐5p could also modulate radio‐resistance of NPC through targeting PTEN.47 According to the previous study, let‐7 family could prevent tumor cells proliferation by suppressing c‐Myc expression in NPC and the dysregulation of miRNA let‐7 might be associated with the early formation of NPC.48 Evidence was still limited, but our findings might provide some hints for future investigation.