TSC2 and lymphangioleiomyomatosis: 05); MLPA identified a germline duplication of exon 31–42 in TSC2 in patient ID180; and CMA identified a 2.68 Mb somatic duplication with TSC2 involved in patient ID160 and 9 CN-LOHs in 9 out of the 24 patients with surplus samples available for testing from the 61 LAM patients (S4 Table, Fig 4A and 4B).