The Liang et al. (2018) study analyzed 91 genes in a series of non‐pretreated primary tumors including 156 IBC and 197 stage 3–4 TCGA non‐IBC: Seventeen genes were more frequently mutated in IBC than in non‐IBC, including TP53, NOTCH2, MYH9, BRCA2, ERBB4, POLE, FGFR3, ROS1, NOTCH4, LAMA2, EGFR, BRCA1, TP53BP1, ESR1, THBS1, CASP8, and NOTCH1, and one gene, CDH1, more frequently mutated in non‐IBC. This evidence concerns the gene CDH1 and inflammatory breast carcinoma.