DNM1 and cancer: The physicochemical properties of nanoparticles, including size, surface functionalization, as well as cell type may govern cellular interactions.52 Also, reportedly, endocytosis is dysregulated in cancer and trafficking can be disturbed downstream of oncogenes.53,54 Here, the predominant uptake pathway for the star polymers, irrespective of functionalization or cell type, was dynamin-dependent CME.