Moreover, we determined alterations in the gene expression levels of tumor proteins, TP53, TP73 and PRDM16 (PR/SET domain 16), MEGF6 (Multiple EGF like domains 6), CEP104 (Centrosomal protein 104) and DFFB (DNA fragmentation factor subunit beta), which are in proximity to the TP73 gene locus in chromosome 1p36.32 region. The gene discussed is PRDM16; the disease is neoplasm.