The first set were ALK-addicted neuroblastoma cell lines: (i) CLB-BAR, harboring an amplified ALK locus with a deletion of exon 4 to 11 (Δ4-11) of ALK resulting in an extracellular domain ALK deletion, (ii) Kelly, which harbors an ALK-F1174L mutation and (iii) CLB-GE, which contains an ALK-F1174V mutation, which is located in the α-C-helix of the kinase domain. Here, ALK is linked to neuroblastoma.