There were significant differences in the levels of hypertension (5.56% vs. 18.18%; p = 0.042), diabetes (0.00% vs. 12.73%, p = 0.007), anti-AQP-4 antibodies (31.8% vs. 58.18%, p = 0.009), and the relapse rate (31.48% vs. 67.27%, p < 0.001) between these two groups. The gene discussed is AQP4; the disease is Hypertension.