PRNP and neuroblastoma: Human neuroblastoma (SH-SY5Y) cells expressing reindeer PRNP allele C (deletion; rePrPdel) and allele A (Ser225; rePrPwt) produced similar amounts of PrPC with a similar glycosylation pattern (Figure 2), indicating that PrPC trafficking and post-translational modification with the attachment of N-glycans appears unaffected by the 24 bp deletion.