PDLIM7 and Epstein-Barr virus infection: EBV infection: in most cases, with methods of immunohistochemistry, polymerase chain reaction, and in situ hybridization, the evidence of EBV infection, such as latent membrane protein-1 (LMP-1), EBV-associated nuclear antigen-2 (EBNA-2), and EBV receptor-1 (EBER-1), can be detected among tumor cells.[1] Studies reveal that latently infected cell expressions of EBV and related gene products of EBV, such as EBNA-2, LMP-1, and EBER-1 cause EBV-infected cells to escape the body's immune surveillance without being cleared out by cytotoxic T cells.