A meta-analysis conducted by Li et al[15] confirmed tea or tea extraction could maintain a stable fasting blood insulin level and reduce waist circumference, but there were no statistically significant differences in other indicators such as FBG; another study[17] from Jinyue Yu and colleagues suggested no evidence to support that the consumption of green tea can effectively benefit glycemic control in T2D patients. The gene discussed is INS; the disease is type 2 diabetes mellitus.