By collecting the liver function data, we found that patients in E‐PBC group had higher levels in ALT (293.0 ± 100.1 vs. 118.4 ± 45.2 U/L), AST (163.2 ± 52.8 vs. 131.7 ± 43.1 U/L), γ‐GT (533.0 ± 180.6 vs. 447.0 ± 152.3 U/L), and lower levels in TBil (38.6 ± 14.2 vs. 92.1 ± 38.2 μmol/L), DBil (24.1 ± 8.3 vs. 67.3 ± 23.6 μmol/L), ALP (419.0 ± 142.0 vs. 467.0 ± 91.2 U/L) than L‐PBC group. The gene discussed is GPT; the disease is primary biliary cholangitis.