Small increases (1.3 fold or lower) in the expression of mRNAs for Complex I—NADH dehydrogenase (ndufa1, ndufa3, ndufa6, ndufa7, ndufa11, ndufa13, ndufs7, ndufv1, ndufb8), Complex II—succinate dehydrogenase (sdhb), Complex III—ubiquinol-cytochrome c reductase (uqcr10, uqcr11), Complex IV—cytochrome c oxidase (cox6a2, cox8b) and Complex V—ATP synthase (atp5d) were observed in tumor-bearing mice compared to controls (FDR < 0.05, Table A in S1 File). The gene discussed is ATP5F1D; the disease is neoplasm.