FN1 and neoplasm: To determine if the uptake of MT218 is correlated with the endogenous EDB-FN expression in different tumor xenografts, we evaluated the changes in SNR in the MDA-MB-231 and Hs578T tumor models at 20 min post-injection of MT218 at 0.1, 0.04, and 0.02 mmol Gd/kg (Figure 5).