NCOR1 and hepatocellular carcinoma: However, as seen in HBX negative HCC cell HepG2 (Figure 3B, topmost panel), the NCoR signals in most of the tumor cells in HBV negative HCC tissue section largely overlapped with the nucleus and the perinuclear region with some degree of extension into the cytosole (Figure 4B, panel 1), while the NCoR signals were predominantly visible in the nucleus of normal liver tissue section (Figure 4A, panels 1, 2).