HSPG2 and hepatocellular carcinoma: To investigate whether misfolded conformation dependent loss of NCoR also plays any role in the pathogenesis of HCC, the level of intact NCoR protein in commercially available HBX positive HCC cells (SKHep1, PLC, Snu449, Snu387, Snu398, and Snu423) and HBX negative HCC cells (HepG2) was determined by western blotting assay.