The findings reported in this manuscript are consistent with those finding and suggest that HBX can also create a PML-RARα or MLL1-AF9 like effect on the conformation of NCoR protein through aberrant post-translational modification and transform the liver cells through similar oncogenic gain of function mechanism as observed in promyelocytic and monocytic AML. This evidence concerns the gene NCOR1 and acute myeloid leukemia.