Despite not being a member of the HSP70 family, the small HSPB2 chaperone was recently shown to be associated with neuropathies when disregulated (Yu et al., 2018) and thus may play a role in neuron proliferation, a process shown to be important for acclimation (Matsuzaki et al., 2017). The gene discussed is HSPB2; the disease is neuropathy.