Even though BRD3 inhibitors have not been studied as much as those of the BRD2/4, it has been observed that I-BET151, a pan-BET inhibitor that targets BRD3 (Picaud et al., 2013), halts the progression of the cell cycle and decreases cell proliferation in vitro and in vivo by targeting lncRNA HOTAIR in glioblastoma (Pastori et al., 2014). This evidence concerns the gene BRD3 and glioblastoma.