CSF1R and liver disorder: Steroids (e.g., Dexamethasone), IL-4, IL-10, secretory leukocyte protease inhibitor (SLPI), prostaglandin E2 (PGE2) and colony-stimulating factor 1 receptor (CSF-1R) agonists are the promising therapeutics targeting different immuno-modulatory pathways that have been explored for macrophage reprogramming in liver diseases (90).